"Come to me, all you who are weary and burdened, and I will give you rest. Take my yoke on you, and learn of me; for I am meek and lowly in heart: and you shall find rest to your souls..." Matthew 11

'Means that our Saviour has invited all that labor and are heavy-laden, to come unto him. Worldly men burden themselves with fruitless cares for wealth and honor,laboring for happiness and sensual pursuit of pleasures. Those who labor to establish their own righteousness labor in vain. The convinced sinner is heavy-laden with guilt and terror; and the tempted and afflicted believer has labors and burdens. Christ invites all to come to him for rest to their souls.' Matthew Henry Commentary

What it does not mean is that we are to have no burden for the lost. It does not mean we are to cast our cares upon Him and walk away content and joyfully secure in our own salvation. It does not mean we should find rest for our souls as thousands die daily to be eternally separated from God.

“Every true Christian should be exceedingly earnest in prayer concerning the souls of the ungodly, and when they are so, how abundantly God blesses them, and how much the church prospers. But beloved, souls may be damned, yet how few of you care about them! Sinners may sink into perdition, yet how few tears are shed over them! The whole world may be swept away by a torrent down the precipice of woe, yet how few really cry to God on its behalf. How few men say, ‘Oh that my head were waters and mine eyes a fountain of tears, that I may weep day and night for the slain of the daughter of my people!’ We do not lament before God the loss of men’s souls, as it well becomes Christians to do.” Charles H. Spurgeon